This song tells the story of a singer trying to find Ophelia, who has left town quickly. While their relationship isn't explicitly defined, some interpretations suggest she might be an old friend or a lover. The lyrics hint at a deeper, possibly illicit connection, with lines like "Honey, you know we broke the rule" and "Was somebody up against the law?". One reading suggests Ophelia might be a Black woman in a Southern town, forced to flee due to societal attitudes towards interracial relationships with the white singer. This song, from The Band's 1975 album Northern Lights – Southern Cross, carries a Dixieland flavor and plays like a search for a lost connection, tinged with a sense of urgency and unspoken history.